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Voisin devotes these lectures to the consideration of die various forms of mental derangement, on the basis of the changes occurring in the brain cells; and, while it is as yet a question whether, with our present knowledge, we can study insanity solely from this point of view, there can be no doubt that our work for the future must have for its object the endeavour uk to discover the relations which the various and complicated mental phenomena bear to the structural alterations which have now been so abundantly demonstrated to exist.